Programmübersicht
Neue wissenschaftliche Erkenntnisse und aktuellste Produktentwicklungen aus der Industrie finden in unseren Vorträgen der Scientific Conference und des Forum for Innovations ihren verdienten Platz.
Donnerstag
14. Oktober 2021
Spoken Language: English Category: Sustainability / Economic Sustainability The presentation will focus on the follow-up to the Detergents Evaluation, which was published by the European Commission back in 2019. In particular, it will present and elaborate on the concrete actions that the European Commission has taken to address the weaknesses that were identified in the above mentioned evaluation and will attempt to provide a forward looking view into how the Detergents Regulation could look like in the future.
Spoken Language: English Category: Sustainability / Environment, Social Sustainability, Economic Sustainability Sustainability with its three pillars - ecological, social, and economic - has long been an issue for the professional cleaning and disinfectant industry. The products and services of the members of the Industrial Association Hygiene and Surface Protection (IHO) are key to ensuring hygiene as well as maintaining value. They provide a major contribution to a sustainable economy and contribute in particular to the circular economy. The Detergents Regulation, the BPR, REACH, CLP and national standards already provide a legal framework that guides the PC&H industry towards sustainable action. Nevertheless, in light of new regulations such as the European Green Deal, the question arises as to how the industry's level of sustainability can be mapped quantitatively and qualitatively. To provide an answer to this question, the members of the IHO founded a Sustainability Working Group in 2020. The working group is still in the initial phase of developing tangible and comparable sustainability criteria for the PC&H industry. Currently, the group is assessing the status quo in terms of sustainability and trying to develop metrics that could serve as a benchmark for the PC&H industry. As a basis for this project, the working group first looked at the UN Sustainable Development Goals (SDGs) to identify common goals. On the one hand, the presentation provides an insight into the industry's contribution to the circular economy based on concrete examples from the various industries represented in the IHO, and on the other hand, it gives a first insight into the current process, thoughts, and ambitions of the Sustainability Working Group.
Spoken Language: English Category: Sustainability / Environment The Chemicals Strategy for Sustainability (CSS) forms part of the European Commission’s Green Deal and represents the most substantial overhaul of chemicals policy in almost twenty years. It strives for a ‘toxic-free environment’, avoiding harm to humans and to the planet, whilst maximising the contribution of chemicals to society and making EU industry globally competitive in the production and use of safe and sustainable chemicals. A.I.S.E., as the voice of the detergents, cleaning and maintenance products industry, shares the goals of the CSS to prioritise the protection of human health and the environment. Chemical ingredients are essential to safe and effective cleaning and hygiene products, so A.I.S.E. has made it a top priority to contribute the industry’s insights and expertise to ensure the CSS succeeds in contributing towards the zero pollution ambition whilst fostering an innovative and sustainable future for our sector. On the first anniversary of the publication of the CSS, A.I.S.E.’s Scientific & Regulatory Affairs Director Jan Robinson will present an overview of its progress so far and the engagement of the detergents industry to deliver on its objectives.
Spoken Language: English Category: Sustainability / Environment The Green Deal is the programmatic centerpiece of the EU Commission's work. It aims to achieve the transformation of the economy and society toward greater sustainability and environmental protection. In addition to far-reaching climate and energy policy targets and their implementation, additional ambitious measures are planned - above all in chemicals policy, the circular economy and the promotion of biodiversity. Almost all measures of the Green Deal have a direct or indirect impact on the business activities of the chemical-pharmaceutical industry. The lecture gives an overview of the goals and measures of the Green deal. In total, there are more than 50 measures that are summed up under the umbrella of the Green Deal. Some measures will be examined in more detail in the lecture. This is accompanied by a rough prioritization of the measures from the perspective of the chemical industry. The transformation of the industry into a circular- and CO2-neutral industry is a major task that needs to be tackled. The design of the measures is therefore of particular importance.
Spoken Language: German Category: Sustainability / TBA
Spoken Language: English Category: Sustainability /TBA
Spoken Language: English Category: Sustainability / TBA
Spoken Language: English As we know from brain research, all mental activity – to perceive, think, feel, plan, want, etc. – leaves traces in the brain. This is because mental activity is due to neuronal activity, i.e. nerve cells passing electrical impulses between one another other via physical connections (synapses). This changes the very connections through which signals pass by making them stronger. In contrast, connections that are not used get weaker. Thus, the processing of information changes the connections in the hardware doing the processing. This is called the memory, i.e., the storage of information. Therefore, there is no such physical separation between the processing and the storing information in the brain. In contrast, computers consist of a special-purpose chip (or a few of them) that process information – the so-called central processing unit (CPU). In addition to this processing unit, there is a “hard disk” (or another chip) that stores information. Thus, the processing and the storage are two distinct processes that happen within two separate structures. The CPU of the computer does not increase capacity or speed when the computer has downloaded information into memory. In contrast, brains cannot and do not download information, but constantly change by processing information – a process we call “learning”, the result of which is increased mental capacity. On the basis of this fundamental understanding, we can conclude, (1) that the more the brain processes, the more it stores. (2) The more information the brain has stored, the better it can process information in the same domain. (3) Whenever we “outsource”, i.e. let the computer do the work for us, learning does not take place. (4) As a result, our mental capacity does not increase and may decrease. (5) Outsourcing early in life, when basic implicit and explicit learning takes place in many domains, is a fundamental mistake, as it decreases mental capacity. (6) The more is learned in early life, the easier it is to continue learning throughout the entire life. (7) Mental capacity is the foundation of “Lifelong learning”. It is attained during the educational period of the individual, i.e., from the age of 0 to about 25 years.
Spoken Language: English
Visit the virtual booths in the virtual exhibition and listen to the "Exhibitor Slots" in room 1-4.
Spoken Language: English Category: Personal Care / Skin Care Did you know that our skin needs the light to be healthy and produce the essential hormone Vitamin D (the sun vitamin)? Did you know that vitamin D levels are critically decreased due to in-house habits, and an excess of sun protection cream use? Nowadays, VitD levels are very low which is crucial for our health. A topical VitD booster would be a very interesting counteracting strategy to start living in ‘more exposed’ routines. Based on plant cell culture technology, Vytrus has investigated and developed an active that opens a new paradigm in skin ageing: plant stem cell glycoconjugates that stimulates VitD synthesis by optimizing the skin microenvironment. Promoting this optimized microenvironment by a strong spatial organization of cell membranes, light use maximizing, and boosting of water deep reserve. The active is made from Lithops pseudotruncatella cell cultures through the company newest Technology Platform: the Phyto-Glucidic Fractions (PGFs). It ignites the VitD production to compensate the lack of sun exposure and strengthen, revitalize, volumize, and glow the faded skin. Several innovative in-vitro an in-vivo tests have demonstrated a multi-activity and holistic approach in the field of topical VitD synthesis induction: In-vitro tests: -Antioxidant and anti-collagenase activity -Fibroblast proliferation -Induction of VitD and Lumisterol synthesis in both keratinocytes and fibroblasts In-vivo tests: -Skin glow and dewiness boosting (polarized light) -Stimulation of skin-deep layers tissular water (1mm depth) measured by a Hyperspectral camera, the latest in photonic medical device to measure the optical properties of the skin -Evaluation of water retention capacity increase -Normalization of skin respirometry (Oxygen and CO2 production) -Facial volume increase linked to the increasing in water turgor (Active stereoscopy)
Spoken Language: English Category: Cosmetic Science / Skin Care Sunscreens are a still rising cosmetic product category, designed to prevent premature skin aging and the generation of skin cancer. In recent years, new requirements on sun protection and proof of protective capabilities have been established. These are mainly based on the discovery that 50% of the free radicals, formed by solar irradiation, arise in the visible and infrared spectral regions. If skin is exposed to UV/VIS light, up to a dose necessary to produce the optimal amount of vitamin D, predominantly ROS radicals are formed. Any further increase of the dose towards the MED leads to a dominance of lipid peroxide radicals (LOS) which are known to have strong damaging effects. Sunburn starting at one MED represents visible skin damage. Considering the role of free radicals in these processes, sunscreens must go beyond the UV, providing light protection in the complete solar spectrum.. Since there are no colorless filter substances in the VIS/IR regions, a protective function can be created using antioxidants and pigments. Studies on test subjects of the same age (50 years) show that people with a high antioxidant concentration in their skin developed less signs of skin aging than people with a low antioxidant status. Looking at the formation of free radicals in different skin types, it could be shown that people with skin type IV–V exhibit significantly fewer free radicals in the UV region than people with skin type I–III. In the infrared spectral region, it is the other way round. A second methodical trend in sun protection is to replace the human volunteers-based invasive SPF determination by non-invasive methods. Latest developments based on a „photon banana”, permit to detect backscattered light from skin treated with sunscreen and thus to determine the SPF non-invasively.
Spoken Language: English Category: Personal Care / Other Creating an emotional link between the user and the cosmetic product is one of the most powerful ways to build loyalty. At the intersection of neuroscience, computer science and marketing, it involves a multifactor approach including company image, brand values, packaging. Focusing on the formula, color and perfuming are well known as an integral part of the customer's emotional experience. Providing evidence and characterizing the impact of the “nude texture” is more challenging, especially if one seeks to determine the influence of the different ingredients and to identify those driving the emotions. The purpose of this work was to explore different methodologies, using verbal and non verbal measurement techniques, to collect the emotional potential of minimalist skin care formulas and pillar ingredients. Different methods were investigated under the supervision of neuroscience experts, such as prosody and gesture, Sense & Story journey, R3m score©, Innovative electrophysiological real-time evaluation. An innovative in vitro fully human innervated reconstructed epidermis also allowed to investigate nociception and physiopathology response. The results demonstrated that the “nude formula” plays a role on emotional potential and type of emotions generated while changing one ingredient mostly acts on emotions intensity (excipient). Verbatim provided contrasted answers depending on the protocol. The in vitro model substantiated physiological effects of ingredients on human skin sensory neurons activity.
Spoken Language: English Category: Personal Care / Other /Hair Care Hair aging is characterized by greying, loss and thinning of hair. It is considered as an aesthetic problem and might cause major psychological distress in affected individuals. Therefore, the cosmetic industry is looking for mild and natural treatment options. We investigated an extract of the alpine plant Edelweiss (Leontopodium alpinum, var. Helvetia, particularly rich in leontopodic acid), for its ability to work against hair aging. Our data on human hair follicles ex vivo show that the extract is able to significantly prolong the hair growth phase anagen and to increase keratinocyte proliferation in the hair matrix, both associated with hair growth mechanisms. In addition, there was a donor-dependent increase in the hair follicle’s melanin content, suggesting positive effect on hair pigmentation. Regarding anti-hair loss, we performed a 150 day placebo controlled clinical study on Caucasian volunteers (both male and female, age 18-65, 30 volunteers per group). We found a significant increase in hair density (Trichoscan) over time and against placebo formulation (+ 13%, p = 0.0002) which was underlined by an increase in anagen to telogen ratio (Trichogram) (+ 6.7%, p = 0.06 vs placebo), which is in line with the data on hair follicles. In a similar manner, we performed a 120 day placebo controlled anti-hair greying clinical study, on Caucasian volunteers (both male and female, age 18-45, 30 volunteers per group). Trichoscan analysis showed a significant increase of pigmented hairs for the Edelweiss extract over time (+13%, p = 0.020), and against the placebo group (p = 0.026). In summary, we provide evidence that an extract of the alpine plant Edelweiss (ALPAFLOR® EDELWEISS CB) has a solid hair anti-aging effect ex vivo and in vivo.
Spoken Language: English Category: Personal Care / Other / Skin Care and Skin Health in Times of Changing Lifestyle Frankincense has been used for thousands of years in a wide variety of cultures for its wide range of effects, up to and including medicinal applications, with particular emphasis on its anti-inflammatory properties. A large number of studies showed that an application of 3-O-acetyl-11-keto-β-boswellic acid (AKBA) has strong anti-inflammatory effects and is therefore not only an interesting natural ingredient in cosmetics, but also in the medical field (1). Premature aging of the skin in particular can be due to both external causes such as negative environmental influences (UV radiation, pollutants, chemical irritants) and internal causes such as silent inflammatory processes caused by oxidative stress. Aging and also inflamed skin is reflected in the loss of elasticity, of wrinkling, dryness and a susceptibility to frequent or localized redness as well as discomfort with the sensation of tense or burning skin. The main disadvantage of dermal application of the lipophilic active ingredient AKBA is its low uptake and penetration into deeper skin layers. By encapsulating the frankincense extract in an O/W nanoemulsion, the Lipo-Tops, efficient accumulation even in deeper skin layers was demonstrated six hours after application, favoured by small particle sizes of the Lipo-Tops (2). Furthermore, the stability of the carrier system and of the encapsulated boswellic acid AKBA over a period of three months was demonstrated as well as their biocompatibility as a prerequisite for a safe and non-irritating application on the skin (3). Lipo-Tops Boswellin are suitable for a variety of applications such as care of aging skin, oxidative stress, exceptional skin stress and also in medical skin care. Literature 1. Ammon H.P.T.; „Weihrauch – Anwendung in der westlichen Medizin“ Springerverlag 2018 2. Karl B. et al.; Poster DPhG Tagung Hamburg, Oktober 2018 3. Karl B. et al.; International Journal of Pharmaceutics 587 (2020) 119635
Spoken Language: English Category: Cosmetic Science / Other / Boosting Vitamin C Vitamin C darling in skin care is a great anti oxidant , helps fibroblasts to produce and secrete collagen , in melanocytes it reduces tyrosinase activity . Vitamin C is desirable for the skin with specific transporters : STVC 1 and 2 . However ascorbic acid ( AA ) is very fragile and can be easily oxidized , therefore deactivated . Skin has also OCTN 's , seen as carnithine transporters . In fact , OCTN1 , present in all cells of the skin and in the nucleus membranes transports Ergothioneine ( EGT ). Is there a synergy between ergothioneine and ascorbic acid ? EGT is produced by fermentation , reactions and purification . First test was to mix EGT with AA at ratios of 1 to 10 AA , 37 C , 5 hours . Without EGT , ascorbic acid is oxidized in 5 hours but 75 % of ascorbic acid is not with EGT. Alloxan was added to generate free radicals to oxidize ascorbic acid in 3 hours ; 40 % is not oxidized with EGT . A formula , after a week at 45 C , with 1% Ascorbic acid turned yellow but did not adding 0.005 % of EGT . EGT was added to Magnesium ascorbyl phosphate at 1 % in fibroblasts . 16 hours later there was 3 times more ascorbic acid intact in the cells with or without EGT . EGT / vitamin C at 1 / 100 doubled the production of collagen 1 , multiplied by twelve the production of collagen 3 compared to no use of EGT . EGT / Vit C at 1 for 100 on melanocytes cut melanisation in half compared to no use of EGT . These experiences confirmed the synergy and boosting of EGT on Ascorbic Acid.
Spoken Language: English Category: Personal Care / Other Cannabidiol (CBD), a major phytocannabinoid found in Cannabis sativa L., has gained increasing interest in the world of cosmetics. Unlike tetrahydrocannabinol (THC), another cannabinoid found in hemp plants, CBD is not psychoactive and offers numerous health benefits, including anti-anxiety, anti-inflammatory, and soothing properties as well as the potential to reduce pain sensation, nausea, and seizures. In the skin, CBD exert effects on pain sensation, inflammation, and the regulation of epidermal homeostasis. Whereas the biochemical function of CBD is well understood for systemic applications, the effects in topical applications are still less clear. In our own studies, we looked at the gene expression in skin explants after treatment with CBD and could not identify any modulation of specific mechanisms. A combination of CBD and Swiss Stone Pine (Pinus cembra) extract containing high concentrations of Pinosylvin, however, showed synergistic effects on anti-inflammatory and tissue regeneration activities in keratinocytes. In a clinical study, using a CBD nano-emulsion combined with the Pinosylvin-containing extract we found a smoothing effect with a reduction of skin roughness and wrinkles induced by the relaxing properties of the treatment. Moreover, the treatment with CBD and Pinosylvin improved the skin tone by reducing haemoglobin and melanin levels in the skin, an effect that can be attributed to the anti-inflammatory and antioxidant effects of these compounds. Thus, the topical application of CBD or combined synergistic treatments with CBD result in further beneficial and visible effects on the skin that are based on the anti-inflammatory and soothing nature of CBD.
Visit the virtual booths in the virtual exhibition and listen to the "Exhibitor Slots" in room 1-4.
Spoken Language: English Category: Fragrance Fragrance is a decisive factor for consumers when purchasing home and personal care products due to the experiential element it adds. However, consumers' growing interest in health and wellbeing will create additional scrutiny over the fragrance components in the products they buy over the coming years. Brands and products can adjust their messaging around fragrances to take into account these consumer concerns, but can also communicate the wider benefits that fragrances can provide to help people in their everyday lives. By doing so, brands can encourage people to see greater value in the products they offer. By identifying what consumers want from their products, and why, we can predict the fragrance trends of the future set to unfold in home and personal care space.
Spoken Language: English Category: Fragrance Olfaction is the most primitive sense and is closely linked to brain areas that control memory and emotions. In this regard, odours directly affect our behaviour and mood and, consequently, is a decisive factor in the acceptance or rejection of all kinds of commercial products. Scents are of extreme importance in companies’ branding strategy for creating strong emotional bonds with customers. The characterization of sensorial properties is therefore crucial in product development and optimization. Odours are constituted by (semi-)volatile chemical compounds that, when released by products during unpacking, application, etc., cause an olfactory sensation. Our sense of smell is capable of converting the chemical signals of these molecules into perception. The human nose is very sensitive and detects extremely low concentrations of these compounds, even below the detection limits of advanced analytical techniques. Furthermore, laboratory instruments are not able to interpret how the smell of products is perceived by consumers. For this reason, a wide range of sensory analysis methods are used nowadays to evaluate the performance and perception of consumer products. Depending on the aim of every particular study, sensory tests can be complemented with high throughput instrumental analysis, such as gas chromatography and mass spectrometry with an odour port (GC-Sniffing-MS), for example to identify and quantify the presence of specific wanted or unwanted odorant molecules. The present communication provides an overview on the implementation of joint sensory and chemical approaches for the odour characterization of personal and home care products. State-of-the-art methodologies on the evaluation and performance of specific products based on odour descriptive analysis, quantitative studies, hedonic testing, discriminative assessment, and on the identification of volatile organic compounds via GC-Sniffing-MS are discussed. Some case studies on the strength of integrating sensory assessment and chemical analysis are also presented.
Spoken Language: English Category: Home Care Our presentation at the SEPAWA® CONGRESS 2021 will deal with the predicted requirements and regulative measures of the “EU Chemical Strategy for Sustainability” to be considered by our member companies. After an overview providing the major cornerstones and the state of the art of the debate the assumed consequences for the supply-chains of the cosmetic and of the detergent industry will be outlined.
Visit the virtual booths in the virtual exhibition and listen to the "Exhibitor Slots" in room 1-4.
Visit the virtual booths in the virtual exhibition and listen to the "Exhibitor Slots" in room 1-4.
During the SEPAWA® CONGRESS, SEPAWA® e.V. and also the GDCh organizes a Scientific Poster Session. Authors have the opportunity to present their poster. Find further information on the page: Poster Presentations